Anandhi made her acting debut in Telugu film Maruthi Dasari's Bus Stop in 2012, a positive critical and commercial response at the box office. Within two days of release of the film, she was offered the lead role opposite Varun Sandesh in his next venture Priyathama Neevachata Kushalama and began filming later in the year. She was next seen in Vijay Maddala's Green Signal, the film garnered negative reviews. She made her debut in Tamil with Poriyaalan. Then she featured in Prabhu Solomon's directorial venture Kayal, which did well at the box office. In 2015, Anandhi's first release was in A. Sarkunam's Chandi Veeran. Anandhi then worked on the adult comedy flick Trisha Illana Nayanthara, the film, however, became a large commercial success at the box office and Anandhi later helped promote the release of the film's Telugu version. Her latest release, Vetrimaaran's crime drama film Visaranai, which did well at the box office.Her ongoing projects are Faisal, Pandigai, Enakku Innoru Per Irukku.