Anu Hasan was born to Chandra Hasan, elder brother of the National Film Award-winning actor, Kamal Haasan. She was educated at St. Joseph's Anglo Indian Girls Higher Secondary School, Trichy and earned a MSc degree in Physics and Management from Birla Institute of Technology and Science (BITS), Pilani, Rajasthan. She made her film debut in the critically acclaimed Indira (1995) and has since appeared in many Tamil films, playing minor roles. By 2000, she ventured into television, acting first in the series Anbulla Snehgidhiye, which was adapted from Chitra Banerjee Divakaruni's award-winning novel Sister of My Heart. She then starred in a number of TV series like Avan Aval Avargal, Ammaavukku Rendula Raagu and Vivahita (Malayalam), following which she turned anchor for the celebrity talk show Koffee with Anu aired on STAR Vijay. In 2014 she joined the Ask How India social movement and made a series of videos pertaining to social issues. In addition, Anu has worked as a dubbing artiste, lending her voice for many non-Tamil-speaking actresses, including Raveena Tandon, Preity Zinta and Geetu Mohandas.