Dhanya Mary Varghese was born to Varghese and Sheeba. She has a younger brother, Dikson. She completed schooling at St. Josephs Higher secondary school and M.K.M. Higher Secondary School, Piravom. She is the product of famous institution Kalabhavan. She pursued bachelors from St. Teresa's College in Kochi.She came to the Malayalam movie industry as a junior artist, She was one of the group dancers in the song Thottuvilichalo.. in the movie Swapnam Kondu Thulabharam.She made her acting debut in the Tamil film Thirudi and later debuted in Malayalam through Nanma directed by Sharath Chandran Vayanad. She rose to prominence through her role in Thalappavu. She later acted in several Malayalam films such as Vairam: Fight for Justice, Kerala Cafe and Nayakan. She was one of the anchors in "Vanitha Asianet-Film awards 2009". She appeared on several Malayalam musical albums. As of 2016, Dhanya is serving as director of sales at real estate development company Samson and Sons, where John Jacob is managing director. Dhanya got engaged on 14 November 2011 with John, Winner of Tharolsavam program in Kairali channel. John and Dhanya got married on 9 January 2012 at Mateer Memorial Church, Trivandrum. After marriage she retired from film industry. The couple was blessed with a baby boy Johan on 13 July 2013.