Lakshmi Menon was born to Malayali parents Ramakrishnan, a Dubai-based artist and Usha Menon, a dance teacher. She studied at the Bharatiya Vidya Bhavan's Munshi Vidyashram in Kochi, where her mother also works. After completing 12th, she got admission in Sacred Heart college Kochi for BA literature.
In 2011, Malayalam director Vinayan, who saw her during Bharatanatyam telecast, cast her in his film Raghuvinte Swantham Raziya, when was in her eighth grade. Soon after, she played the lead along with Vineeth in another Malayalam film titled Ideal Couple, directed by Ali Akbar. After she began acting in Malayalam cinema, she was featured on the cover of a magazine and it caught the attention of director Prabu Solomon, who cast her in Kumki . Director Prabhakaran offered her the lead role in Sundarapandian. Suseenthiran's action-drama film Pandianadu, all her four Tamil films, released in a span of one year were box office hits. She also enacted in Naan Sigappu Manithan, Manja Pye Jigarthanda, Komban, Miruthan and so on. And also, she performed as a singer in films like Oru Oorla Rendu Raja, Saahasam and Kuzhambi. Her upcoming project is Sippai.