Manjima Mohan is the daughter of cinematographer Vipin Mohan and dancer Kalamandalam Girija. After completing her Plus Two at Nirmala Bhavan Higher Secondary School, Thiruvananthapuram, Kerala, she pursued a B.Sc. degree in Mathematics from Stella Maris College, Chennai, Tamil Nadu. In 1998, Manjima made her acting debut as a child actress in Malayalam films. Her first role was in Kaliyoonjal in which she portrayed the younger version of Shobana's character Gauri. She continued to work as a child artist for three years in films including Priyam and Madhuranombarakattu, the latter earning her the Kerala State Film Award for Best Child Artist, besides hosting Hai Kids, a television call-in show for children. After Thandavam, she took a break from acting to concentrate on her education. Her debut movie as a heroine in the film, Oru Vadakkan Selfie, which was directed by G. Prajith and scripted by Vineeth Sreenivasan, featured Manjima Mohan as the female lead. The film opened to positive reviews and became the first major box office hit in 2015. Upon Oru Vadakkan Selfie's release, Manjima landed her first Tamil film, Achcham Enbadhu Madamaiyada. Its director Gautham Menon, who was impressed with her work in Oru Vadakkan Selfie, cast Manjima as the female lead. Her on-going projects are Achcham Enbadhu Madamaiyada and Sahasam Swasaga Sagipo.