Remya Nambeesan was born to Subrahmaniam Unni, a former theatre artiste, and Jayasree. Her father was an active member of troupes such as "Jubilee" and "Harishree". She has a brother, Rahul, music director in the Malayalam movie Philips and the Monkey Pen and a playback singer in the film Thattathin Marayathu. Remya studied Communicative English at the St. Teresa's College, Ernakulam. Having learned carnatic music from her childhood, she has sung several numbers for devotional albums on Chottanikarai Bhagavathi.
Remya first appeared as a child artiste in the critically acclaimed drama film Sayahnam in 2000. She further played minor supporting roles in the following years in films including Narendran Makan Jayakanthan Vaka, art film Sthithi, Gramaphone and Perumazhakkalam. She played her first leading role, in 2006 film Aanachandam which went unnoticed soon after its release. The next release, Chocolate featured Remya as one of three leading females, become a high commercial success. She played the female lead in Saarai Veerraju, Aattanayagann and played a minor supporting role in Nammal Thammil. As a singer, she has since sung playback for several films including her own films like Bachelor Party, Up & Down: Mukalil Oralunduand Arikil Oraal which she has acted in and for films she was not part of, like Thattathin Marayathu and Amen. She has sung for the Telugu film Telugabbai, for the Tamil film Pandiya Naadu and will be singing for a Kannada film. In 2014 she sung an Ayyappa devotional song, "Muttath ninnu Chirikkum", which garnered 1.5 lakh hits in you tube.Her upcoming movies include Style King, Aalathoorile Ethiri Vettam.