Reshmi Menon was pursuing Visual Communication at Women's Christian College, Chennai. She accompanied her friend to the auditions for thePrakash Raj production, Inidhu Inidhu (2010), when she herself got the opportunity to essay a lead role in it. Accepting the offer, she shot for the film while still studying, revealing that she had to skip classes at WCC to work in the film. Reshmi was one of several newcomers to make their acting debuts in Inidhu Inidhu. A remake of the Telugu film Happy Days. After Inidhu Inidhu, Reshmi had shot for an independent film titled Om Obama directed by Janaki Vishwanathan. The film was shot over a period of 35 days in 2010, but remains unreleased. In 2011, she had her second release, Theneer Viduthi. The film, a rural comedy set in Bodinayakkanur, fetched mixed reviews. Her next release, the comedy-thriller Burma, came three years after Theneer Viduthi. Burma received generally favorable reviews and her performance was also well received, although critics felt that her role was insubstantial. Her latest release was fantasy thriller Urumeen and psychological thriller Natpathigaram 79. Her upcoming movie is Hyderabad Love Story. Reshmi Menon got engaged with actor Bobby Simha on 8 November 2015.