Sadha was born in a Muslim family to Sayed and Anju. Her father is a doctor and her mother is a bank executive. She did her schooling in Ratnagiri's Sacred Hearts Convent High School and then moved to Mumbai. She had completed her first semester in her Engineering in Information Technology at SNDT College of Engineering, Mumbai. She also is a trained Kathak dancer.
During her schooling, she was offered director Teja's teenage love story Jayam in Telugu which went on to become one of the biggest blockbusters of that year. After making a remarkable debut with Jayam, Sadha appeared in the Tamil movie Anniyan opposite Vikram directed by Shankar, which is her most successful movie to date. Since then, she has appeared in a number of films across movie industries in India, in different languages including Monalisa in Kannada and Click in Hindi. Her upcoming films are Nenu Tanu Aame and Madha Gaja Raja.