Saritha made her acting debut through Maro Charithra, a Telugu film opposite Kamal Haasan, directed by K. Balachander. She received more offers in Tamil films mostly directed by Balachander. Some of her films include Thappu Thalangal, Idi Katha Kaadu, Vandichakkaram, Netrikan, Agni Sakshi, Puthukavithai, Kalyana Agathigal and Achamillai Achamillai. Her performance in Vandichakkaram and Achamillai Achamillai won her Filmfare Best Tamil Actress awards. Saritha has also worked as a voice actor in Kannada, Telugu and Tamil films. She has lent her voice to other actresses including Madhavi, Soundarya, Ramya Krishnan, Nagma and Vijayashanti. She won Nandi Award for Best Female Dubbing Artist for her voice to Soundarya in Maa Ayana Bangaram (1997) and Anthapuram (1999). Her first marriage was with Telugu actor Venkata Subbaih in 1975 and later got divorced n 1976. Her Second Marriage was with Malayalam actor Mukesh on 2 September 1988 and has two sons Shravan & Tejas. The couple got divorced in 2011. Saritha is now staying with her son Shravan in a separate house at UAE, Dubai. She also acted in Television serial.