I. V. Sasi is married to Malayalam actress Seema on 28 August 1980. He met her on the set of his film Avalude Raavukkal. Ever since, she has been his favorite heroine. They have worked together in more than 30 movies. He has two children, daughter Anu and son Ani. Anu has acted in Symphony, directed by her father.Anu got married to Milan Nair on 10 December 2010. Ani was a student of Visual Communication at Loyola College, Chennai and is an aspiring director himself. I. V. Sasi lives with his family in Chennai. He is known for his South Indian films of the 1970s, 1980s, and 1990s, primarily Malayalam films, although he directed Hindi films during the 1980s as well.
He directed his first film at the age of 27. He started his directorial career officially with his first film Ulsavam. He introduced Mammootty as a hero in his film Thrishna. He also introduced Jose. He went on to direct one of Mohanlal's biggest hits, Devaasuram, which was scripted by Ranjith. He has directed films in several other languages, such as Hindi, Telugu, and Tamil. He has directed Kamal Haasan in films like Guru, Allauddinum Arputha Vilakkum, Karishma and Eeta.