Singampuli was born on 6 July 1968 in Theni. After studying engineering in Bangalore, he arrived in Chennai looking for a career in films. During his stint as an assistant director with Sundar C, Singampuli suggested the original plot point of Unnaithedi to the director and Sundar wrote the script of the film within a week, before discussing the line with actor Ajith Kumar. Subsequently he agreed terms to work in the 2002 action film Red, a story telling the tale of a Madurai based revolutionary. In 2005, he made the kidnap comedy film Maayavi featuring Suriya and Jyothika, winning acclaim for his work.